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The product is a neutral polysaccharide produced in the process of culturing Aureobasidium pullulans. 3 glucose through α-1,4 glycosidic bonds to form maltotriose, and then repeated bonding through α-1,6 glycosidic bonds to make the structure of the pullulan.

Capsule drugs are used frequently in life. However, in actual production, the problem of softening of the capsule is often encountered, which is usually happened in spring and summer. The main reason is that the gel cap is not properly stored, which is affected by the temperature or adsorbs moisture in the air.

This standard specifies the specifications, technical indicators and requirements, test methods, inspection rules, criterion rule and requirements of product packaging, labeling, transportation and storage of empty enteric gelatin capsules.This standard is applicable to empty hard capsules made of gelatin and auxiliary materials and suitable enteric coating materials, divided into enteric-coated capsules and colonic enteric-coated capsules, gelatin and enteric materials should meet medicinal requirements.

This standard specifies the specifications, technical indicators and requirements, test methods, inspection rules, criterion rule and requirements of product packaging, labeling, transportation and storage of empty HPMC capsules.This standard is applicable to empty HPMC hard capsules made of HPMC and auxiliary materials and HPMC should meet relevant requirements.

Conventional capsules are generally divided into two broad categories, hard capsules (for powder filling) and soft capsules (for filling oily oils, vitamins and other oily liquids). The liquid-filled hard capsule adopts a two-section structure and is made of gelatin or HPMC as a material for filling a liquid medicine.

This standard specifies the specifications, technical indicators and requirements, test methods, inspection rules, criterion rule and requirements of product packaging, labeling, transportation and storage of empty pullulan capsules.This standard is applicable to empty pullulan hard capsules made of pullulan and auxiliary materials and pullulan should meet relevant requirements.

This standard specifies the specifications, technical indicators and requirements, test methods, inspection rules, criterion rule and requirements of product packaging, labeling, transportation and storage of empty gelatin capsules. This standard is applicable to empty hard gelatin capsules made of gelatin and auxiliary materials. Gelatin for capsules should meet the standard.

Improving the quality of drugs is a problem that cannot be ignored in the capsule pills production and research and development of and new drugs. How to improve stability can find solutions based on the influencing factors mentioned in the previous article. In addition to the stability of the drug prescription design, the pharmaceutical manufacturer should consider the stability of the drug during the packaging process of the capsule.

this standard specifies the specifications, technical indicators and requirements, test methods, inspection rules, and criterion rule. This standard is applicable to edible empty capsules made of various raw materials and excipients.

Oxygen in the atmosphere can cause oxidation of the drug contained in the capsule. On the one hand, during the filling and fitting process, a small amount of oxygen in the atmosphere will remain in the interior of the capsule along with the air, so that some of the medicine is oxidized.